Objective: The aim of the present study is to examine associations among several family functions and resilience against substance which is begin use in high school students. Method: 145 high school students at risk for substance use participated in this correlational study. Family assessment device (FAD) and a researcher-made questionnaire were applied to assess variables. Data were analyzed by Pearson correlation and multiple regressions. Finding: This study revealed significant associations among family functions (problem-solving, communication, roles, control, emotional involvement and general function) and resilience against substance use. But emotional responsiveness was inconsistent with them. Results of multiple regression showed that the emotional involvement can Predict respectively 13% of the resilience against substance use variance (p<0/0001). Conclusion: The more the family functions is healthy and favorable, the more probability of offspring becomes resilient in the face of substance use.
