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Objective: Experiencing stress and emotional disturbances due to ending and separating from a romantic relationship is one of the most painful events for some people. We aimed to evaluate a repetitive transcranial direct current stimulation (tDCS) protocol on a girl experiencing an unmarried relationship break-up.Methods: We aimed to evaluate a tDCS protocol to the left dorsolateral prefrontal cortex (DLPFC) (10 sessions, 2 mA current intensity for 20 minutes, one session each day) on a girl experiencing an unmarried relationship break-up (In Iran, the year 2022). In order to evaluate the effect of this protocol, the assessment of love trauma (Love Trauma Inventory (LTI), depression (Beck Depression Inventory (BDI-II), anxiety Hamilton Anxiety Rating Scale (HAM-A), Cognitive Emotion Regulation Questionnaire (CERQ) and Positive and Negative Affect Schedule (PANAS) was done at different time intervals, before and after the intervention and follow-up.Results: Repetitive tDCS stimulation protocol with left anodal/right cathodal DLPFC montage may effectively reduce emotional disturbances after the experience of separating from a romantic relationship and lead to improved mood.Conclusion: In order to generalize the introduced stimulation protocol, it is necessary to investigate more in large groups of people who have experienced a romantic relationship breakup.

زمینه: دوران سالمندی یکی از دوره های مهم و حساس هر شخص می باشد، سبک زندگی و نشاط معنوی به عنوان مولفه هایی تاثیرگذار بر اختلال آلزایمر در این دوره سنی می تواند نقش آفرینی کند. مقایسه سبک زندگی و نشاط معنوی در مبتلایان به اختلال آلزایمر با افراد بدون اختلال آلزایمر از نوآوری های پژوهش حاضر بود. هدف: هدف پژوهش حاضر مقایسه سبک زندگی و نشاط معنوی در سالمندان بالای 80 سال با و بدون اختلال آلزایمر بود. روش: پژوهش حاضر از نظرروش علی _ مقایسه ای و به لحاظ شیوه ی گردآوری داده ها پیمایشی بود. جامعه آماری شامل کلیه سالمندان (با اختلال آلزایمر و بدون اختلال آلزایمر) شهرستان قلعه گنج بود. که از بین آنها نمونه ای شامل 80 نفر سالمند در نظر گرفته شد. ابزارهای اندازه گیری پژوهش نیز پرسشنامه سنجش و اندازه گیری سبک زندگی اسحاقی و همکاران (1388)، پرسشنامه نشاط معنوی افروز (1395) که بین افراد توزیع گردید. جهت تجزیه و تحلیل داده ها از آزمون تحلیل واریانس تک متغیره با استفاده از نرم افزار SPSS نسخه 26 استفاده شد. یافته ها: بین گروه با اختلال آلزایمر و افراد بدون اختلال آلزایمر در متغیرهای وابسته ترکیبی سبک زندگی از نظر آماری تفاوت معنی داری بود (54/61 F=؛ 013/0 P=؛ 99/0=لامبدای ویلکز؛ و 02/0 =مجذور اتای تفکیکی). بین گروه با اختلال آلزایمر و افراد بدون اختلال آلزایمر در متغیرهای وابسته ترکیبی در متغیر نشاط معنوی از نظر آماری تفاوت معنی داری بود (72/41 F=؛ 019/0 P=؛ 99/0 =لامبدای ویلکز؛ و 03/0 =مجذور اتای تفکیکی). نتیجه گیری: مطابق یافته های پژوهش، سبک زندگی و مولفه های آن و نشاط معنوی تاثیر مثبتی بر پیشگیری از اختلال آلزایمر در سالمندان دارد و می-تواند باعث کاهش آلزایمر در سالمندی گردد. گسترش مهارت آموزی و اصلاح سبک زندگی و ارتقای نشاط معنوی بخصوص در سالهای جوانی و کودکی و ارتقای روزبه روز آنها در کشور می تواند برنامه مقابله ای خوبی جهت پیشگری از آلزایمر در جمعیت

Recent advancements in neurophysiological recording technologies have led to significant complexities in managing large-scale neural data, creating potential bottlenecks in the storage, sharing, and processing within the neuroscience community. To address these challenges, we developed the Big Neuronal Data Framework (BNDF), a distributed high-performance computing (HPC) solution. BNDF leverages open-source big data frameworks, Hadoop and Spark, to offer a flexible and scalable architecture. We tested BNDF on three large-scale electrophysiological datasets from nonhuman primate brains, demonstrating improved runtimes and scalability due to its distributed design. In comparative analyses against MATLAB, a widely used platform, BNDF showcased over five times faster performance in spike sorting, a common task in neuroscience. This significant speed advantage highlights BNDF’s potential to enhance the efficiency of neural data processing and analysis, making it a valuable tool for researchers navigating the complexities of modern neural datasets. Overall, BNDF represents a promising approach to streamline the handling of extensive neural data in the field of neuroscience.

Objective: The present study was conducted with the aim of designing and validating a pessimism questionnaire in married people.Methods: The research method was based on the applied objective and the mixed research method (qualitative-quantitative). The socio-statistics of the research were all professors and experts of clinical psychology and family counselors of Ardabil province in 2022. Among the statistical population, 15 people (11 men and 4 women) were selected based on the principle of opinion saturation as a statistical sample of the qualitative part, and 250 people (136 men and 114 women) were selected as a sample of the quantitative part as a non-random sampling available (easy access) became Interviews and researcher-made questionnaires were used to collect information. Thematic analysis was used with MAXQDA 2018 software to code the interview texts. Additionally, Cronbach's alpha method, construct validity (convergent and discriminant validity), and partial least squares (PLS) were used to analyze the data from the researcher-made questionnaire using SPSS and SmartPLS software.Results: The results indicated that the reliability and validity of the structure (convergence and divergence) were confirmed at an excellent level, and then the confirmatory factor analysis models were confirmed both in the mode of standard coefficients and the mode of absolute significance (p<0/05). Based on the results of this research, it is suggested that due to the innovation of this questionnaire, this questionnaire should be administered to couples before marriage in counseling centers and psychotherapy under the supervision of experienced professors with university experience and couples with pessimism problems before starting life.Conclusion: The joint should be examined and treated during effective protocols to prevent the problems caused by pessimism, which sometimes leads to the disintegration of the joint life if it is aggravated.

The study reported in this paper aimed at developing and validating a family-based mental empowerment program to enhance cognitive processes, psychological hardiness, and academic performance of slow learners. The present study was fundamental in nature. The statistical population included psychologists and exceptional children's education specialists, family education instructors, and parents of slow learners in Tehran. The sample population consisted of three professors in psychology and exceptional children's education from the University of Tehran, three family education instructors, and three mothers of slow learners, selected through purposive sampling. The validation process of the studied program was carried out in five steps (reviewing theoretical foundations, reviewing previous research and existing programs, developing program content, validating the content, and explaining the program validation). The Delphi method was used for program content development, triangulation and Lawshe's content validity index were employed for content validity determination, and the expert agreement percentage method was used for determining the program’s reliability. The overall content validity coefficient of the sessions stood at 85%, and the program’s reliability coefficient was 86%. The family-based mental empowerment program aimed at enhancing cognitive processes, psychological hardiness, and academic performance of slow learners demonstrated high validity and reliability. Therefore, this program can be used to improve the cognitive and academic status of slow learners.