The purpose of the study was to examine the impact of ICT on entrepreneurship skills of educators in Mazandaran vocational and training centers. The research method was a descriptive survey one. The statistical population included all vocational teachers working at Mazandaran technical and vocational organization amounting to 260 people. Based on Krejcie and Morgam table, 155 people were selected through simple random sampling method. For data gathering, a researcher made-questionnaire consisting 28 closed response in the form of five-choice likert items along with library studies were used. The reliability index of the questionnaire was 0/76. The gathered data were analyzed by the use of SPSS statistical software. The results showed that ICT had an important effect on entrepreneurship skills (Managerial, personal and technical skills) of teachers in technical and vocational centers.