Purpose: The aim of this study was to compare the effectiveness of transcranial magnetic stimulation (tms) and cognitive-behavioral therapy (cbt) in patients with depression in Tehran. Methodology: The purpose of the present study is to apply the pre-test and post-test with control group in terms of semi-experimental research method. The study sample consisted of 60 clients with depression who had been diagnosed by the Psychiatric Commission and admitted to psychology clinics in 2015. They were selected by random sampling and were randomly divided into three groups (two experimental and one control group) in each group of 20 persons. . Experimental groups in one group underwent cognitive-behavioral therapy for 12 sessions and the other group underwent transcranial magnetic stimulation for 20 sessions. Control group received no intervention. Data were analyzed using covariance analysis. Findings: The results showed that there was a significant difference between transcranial magnetic stimulation and cognitive-behavioral therapy in reducing depression in clients (P <0.01). Conclusion: Transcranial magnetic stimulation therapy and cognitive-behavioral therapy are effective in reducing depression in patients referred to psychiatric clinics.
