Purpose: Considering the importance of human resources in e-government and emphasis on administrative health, the aim of this study was to design a model for the development of human resources in e-government with an administrative health approach. Methodology: The present study was applied in terms of purpose and mixed (qualitative and quantitative) in terms of implementation method. In the qualitative part, the research community was experts and managers of government organizations in the field of policy making in Mazandaran province, and according to the principle of theoretical saturation, 17 of them were selected by targeted sampling methods. In the quantitative part, the research community was the employees and administrative managers of government organizations in Mazandaran province, according to Cochran's formula, 303 of them were selected by multi-stage cluster random sampling. The research tool was a semi-structured interview in the qualitative part and a researcher-made questionnaire (84 items) in the quantitative part, whose psychometric indicators were checked and confirmed. Qualitative part data were analyzed by coding method in Maxqda software and quantitative part data were analyzed by exploratory factor analysis and structural equation modeling methods in SPSS and Lisrel software. Findings: The findings of the qualitative section showed that for the development of e-government human resources, there are 5 components of professional development, social cultural development, organizational development, individual development and educational development, and for administrative health there are 7 components of institutional unity, manager's influence, consideration, constructiveness, resource support, morale and emphasis. Scientifically identified. Also, the findings of the quantitative section showed that the factor load and the average variance of the extracted components were higher than 0.50 and their reliability with Cronbach's alpha method was higher than 0.70. In addition, the human resources development model of e-government had a good fit with the administrative health approach, and administrative health had a positive and significant effect on the development of human resources of e-government, administrative health on its seven components, and the development of human resources of e-government on its five components(05/0P<). Conclusion: According to the results of the present study, for the development of e-government human resources, it is possible to provide the basis for the realization of administrative health through the components identified for it, including institutional unity, manager's influence, considerateness, creativity, resource support, morale and scientific emphasis.