Introduction: Students from any country are considered as intellectual and spiritual resources of the country and their issues and problems are important for successful study and providing their physical and mental well-being. The purpose of this study was to investigate the relationship between Spiritual Health and Self-Awareness with Positive-Thinking in second-grade female high school students of district one of Tehran city. Methodology: The present study was a descriptive (correlational) one in terms of method and an applied one in terms of the purpose. The statistical population of the present study was second-grade female high school students of district one of Tehran city in the academic year of 2017-2018. The sample of the study was 100 students who were selected by multi-stage cluster sampling. Data collection was done by Self-Awareness Questionnaire by Fenigstein, Scheier & Buss (1975), Self-Awareness Questionnaire by Oxford Argyle (2001), and Psychological Well-being Questionnaire by Pulotsin and Ellison (1982). For statistical analysis, the mean and standard deviation of descriptive statistics and multivariate regression were used at the level of inferential statistics and the correlation coefficient was used using SPSS22 software at a significance level of 0.05. Findings: The results showed that the relationship between Spiritual Health and Self-Awareness with Positive-Thinking was significant in the female high school students in Tehran city, so that these two variables had the ability to predict Positive-Thinking and were able to explain Positive-Thinking variable to 14.4 percent (P <0.01). Conclusion: Self-awareness and its role in Spiritual Health showed that self-awareness was related to mental and physical well-being.
