درخت حوزه‌های تخصصی

Purpose: It has been well proven that type 2 diabetes is one of the most common non-communicable diseases leading to many complications and mortality every year. The aim of this study was to investigate the effect of resistance training on FTO and PPAR-y gene expression in muscle tissue of obese diabetic rats. Study design: This experimental study was performed on 12 male Wistar rats (10 weeks old and 220±20 g bodyweight). Methods: Animals received 6 weeks high-fat diet and then in order to induce type 2 diabetes an intraperitoneal injection of a single dose of 30 mg/kg freshly prepared streptozotocin (STZ) (Sigma, USA) solved in citrate buffer (pH 4.5) was performed. Diabetic rats were divided into two (Resistance and control) groups randomly. The resistance program included 6 weeks, 5 sessions per week. The muscle expression of FTO and PPAR-γ was measured using the real-time PCR method. Independent t-test and Analysis of covariance (ANCOVA) were applied to compare the means. Results: The muscle mRNA expression of PPAR-γ and body weight significantly increased after 6 weeks of resistance training (p=0.031, p=0.037; respectively) but there was no significant change in the muscle mRNA expression of FTO (p=0.317). Also, blood glucose significantly decreased in the training group compared to the control group (p=0.01). Conclusion: According to the results of this study, it can be noted that 6-week resistance training by decreasing glucose levels and increases insulin sensitivity, and the muscle expression of PPAR-γ plays a prominent role in the control and treatment of type 2 diabetes in obese patients.

Purpose:  Multiple Sclerosis (MS) is an autoimmune disease which is on the rise in recent years especially in Iran. Although there has been much progress in MS treatment, there is no definitive cure for it. Considering high prices of prescription drugs and their serious side effects as well as, impact of this illness on function efficiency of individuals, it seems that exercise training is one of the effective, cheap, and without side effects methods, in improvement of the performance of MS patients. In this regard, the present study aimed to provide comprehensive information on the background and the latest studies conducted to evaluate the effect of various exercise trainings (resistance, aerobic, core stability, Pilates, and combined) on this disease.  Methods :  An electronic search from 1994 to 2022 was performed in the Magiran, SID, PubMed, Google Scholar, and Scopus databases to find published articles. The keywords were multiple sclerosis, physical activity, exercise, training, aerobics, resistance, combined, core stability and Pilates. Different articles were selected and reviewed according to relation with subject. Results: The results indicated that various exercise training with different duration, intensity, and frequency cause different adaptations in people. Furthermore, regular continuous combined exercise training can be more effective than one type of exercise training in improvement and reduction of the symptoms of MS disease. The mechanism of improvement in combined exercise training can be justified due to the benefits of concurrent use of two or more types of training protocols. Conclusions: It can be said that the combined use of exercise trainings is the most useful and effective method for these patients. However, more studies on the best combination of exercise trainings for MS patients should be done in the future.

Purpose: The aim of this study was compares the effects of 10 weeks High Intensity Interval training (HIIT) and moderate intensity aerobic training (MIAT) on serum levels of homocysteine and some cardiovascular risk factors in overweight inactive men. Methods: In this semi-experimental study, nineteen overweight men voluntarily participated in this study and were randomly divided to 2 Groups: High Intensity Interval training (HIIT) and moderate intensity aerobic training (MIAT). Subjects performed training programs for 10 weeks, 3 sessions per week. The levels of homocysteine and lipid profile were measured before and after 10 weeks of training programs. For statistical data analysis, independent and paired t tests were used and considered significant at a p≤0.05.   Results: The results of this study showed that both High Intensity Interval training and moderate intensity aerobic training caused a significant reduction of homocysteine levels (P≤0.05). After 10 weeks of high -intensity periodic exercise, cholesterol levels (p = 0.001), LDL (p = 0.002) decreased significantly and HDL levels were significantly increased (p = 0.001), In MIAT training group, only a significant reduction in cholesterol was found (P=0.006). Conclusion: According to the results of this study, it seems that both High Intensity Interval training and moderate intensity aerobic training have favorable effects in reducing body weight and some cardiovascular risk factors.

Purpose: Skin is the most important organ of the body and maintains its integrity is critical in good health. Severe skin damage is life-threatening and repairing restores its tissue integrity and delay in it endangers health. According to the importance of wound healing and the fact that not treated wounds may decrease quality of life, many studies have investigated the effect of some natural and chemical substance on the length and quality of wound healing to find out beneficial interventions that rapidly and economically treat it. This review aimed to describe the physiology of cutaneous wound healing and some negative and positive factor with a focus on exercise. Methods: An electronic search without any time limitation was performed on the PubMed, Google scholar and web of science databases to find published articles in English. The keywords were wound healing, exercise, and physiology. According to relation to subject, similarities, and differences 48 articles were selected and reviewed. Results: wound healing is a complicated physiology process that consists of four consecutive overlapping stages. Disruption in each stage disturbs wound healing. Many chemical and herbal compounds are used to speed up wound recovery due to their anti-inflammatory property. Exercise is one of the effective factors in wound healing and many studies evaluated effect of different protocol of exercise on it. The results of studies show that aerobic exercise due to its anti-inflammatory and antioxidative effect is a beneficial method in shortening the length of wound healing, especially in aged, fat, and diabetic individuals. Conclusion: Moderate intensity aerobic exercise as a complementary medicine is a good intervention in the treatment of impaired and chronic wounds.

Purpose: The objective of this study is to analyse various articles on the effect of various types of exercise on the angiopoietins family and angiopoietin-like proteins (ANGPTLs). Methods: PubMed, Science Direct, Scopus and Google Scholar databases were searched from 2000 to September 2020. After screening the articles, 19 articles that met the inclusion criteria were studied and analysed. Results: In our body, four types of angiopoietin and eight types of angiopoietin-like proteins have been identified, the functional method of some of them which are still not entirely understood. Angiopoietin-1 and angiopoietin-2 are essential regulators of vascular formation and maintenance. Angiopoietin-1 is found in perivascular and vascular cells within and around smooth muscle cells and plays an important role in growth, vascular stability, and pathological angiogenesis. On the other hand, angiopoietin-2 and angiopoietin-3 are mainly involved in inducing vascular regression, cell death, and inflammation. Angiopoietin-4, like angiopoietin-1, is responsible for the maturation, stabilization, and stasis of blood vessels. Conclusion: Studies show that exercise has a significant effect on increasing capillary density in the human body by increasing angiopoietin as one of the angiogenesis factors. In addition, there are many other benefits such as contribution to fat burning and treatment of coronary artery disease, cancer, asthma, and ischemia. More research is needed on the effects of different types of exercise training on angiopoietins.

Propose: The thyroid hormones (T3, TSH, T4, and FT4) play a role in energy balance and regulation of energy expenditure. The aim present study to investigate the effect of moderate intensity aerobic training on thyroid hormone levels in inactive girls. Method: A total 30 inactive girls students were randomly selected and divided to training group (n=15) and control group (n=15). The training group doing research protocol for four week (three session per week of 70% maximal heart rate), also the control group was not intervened during the study. However, elevation anthropometric index before protocol training study. Blood samples were collected 24 hours before the first and after the last training session. For analysis data used T-test at significant level p<0.05. Results: Results showed a significant reduction of T3 (P<0.05), but no significant change were observed at T4, TSH, FT4 levels after training (P˃0.05). Conclusions: Our results showed that moderate aerobic training of 70% maximal heart rate have minimum effect on thyroid hormones in inactive adolescent girls.

Background: Researchers have studied practical applications of high-intensity interval training and hypoxic training. PGC-1α, IGF-I, and HIF-1α are generated from high-intensity interval training and affect muscle cells. Altitude training also produces HIF-1α, which induces erythropoietin and increases the number of red blood cells. However, due to the limit on training intensity and cycle, it was replaced by normobaric hypoxia training. Purpose: To investigate the effects of 2-day high-intensity interval training on muscular anaerobic metabolism at varying oxygen concentrations for 2 days. Method: Ten subjects performed 2 consecutive days of intermittent hypoxia-hyperoxic training (IHHT); intensity of training was determined by the sprint test results. IHHT comprised 4 sets of 3 repetitions for 40 seconds (4 × 3 × 40 s); the intensity and oxygen concentration were 80% of maximal effort and 13% oxygen for the first and third sets, and were 90% of maximal effort and 21% oxygen for the second and fourth set; participants walked for 3 min wearing an oxygen mask (O2 80%) before each set. Differences in biological parameters between the two days of training was analyzed by t-test. Results: The difference of mean lactate levels between two days were 0.96 ± 0.75 mmol/l at Set 3 (P = .003) and 1.05 ± 1.12 mmol/l at Set 4 (P = .016), respectively. Mean ammonia concentrations at Set 4 were 117.70 ± 29.8 μmol/l for the first day and 94.50 ± 14.45 μmol/l for the second day (P = .057). The difference of heart rate were 4.20 ± 5.05 min-1 at Set 1 (P = .027) and 4.00 ± 5.48 min-1 at Set 2 (P = .046). Conclusions: Two-day intermittent hypoxia-hyperoxic training affected lactate and heart rate.

Background : Low back pain (LBP) can cause changes in muscle activity in affected individuals, making it difficult for them to contract their muscles effectively and engage in physical activities. Manual chiropractic techniques have been proposed as a potential solution to improve muscle orientation and function in individuals with LBP. Aim: The purpose of this study was to investigate the effect of manual techniques on maximum muscle activity electromyography, functional disability, and pain in women with non-specific chronic low back pain. Materials and Methods: Twenty women between the ages of 30 and 50, who had been experiencing NSCLBP for over three months with no history of spinal surgery or postural abnormalities, and were able to perform daily activities after providing consent, were recruited from a sports medicine clinic to participate in the study. In the pre-test, the Oswestry Disability Index (ODI) was used to assess functional disability, and the Visual Analogue Scale (VAS) was used to assess pain levels. Additionally, the maximum muscle activity of the multifidus and lumbar quadratus lumborum (QL) was measured using EMG. Chiropractic manipulation techniques were then implemented in the experimental group, with three sessions per week for six weeks, within the clinic. The same tests were repeated in the post-test. The ANOVA test was used to compare the chiropractic and control groups, with a significance level of α ≤ 0.05. Results : The study results indicate that chiropractic manual techniques were effective in reducing lumbar EMG activity ( P = 0.0001), reducing pain index ( P = 0.002), and improving functional disability ( P = 0.001) significantly. Conclusion : The study findings suggest that six weeks of chiropractic manipulation techniques can induce a feeling of relaxation, reduce pain, and passively strengthen the lumbar muscles. These improvements in muscle condition and functional disability may lead to a reduction in pain experienced by individuals with NSCLBP.

Sports are generally competitive and stressful. Competitive sport anxiety in athletes affects sports self-efficacy. The present study aimed to investigate the relationship of competitive anxiety and mindfulness with sports self-efficacy of male athletes mediated by family cohesion. The statistical population of this descriptive-correlational study covered all male athletes in Masjed Soleyman, Iran in 2021, and a sample of 258 athletes was selected using convenience sampling. The research tools included the Sports Self-Efficacy Questionnaire, Competitive Sports Anxiety Questionnaire, the Mindfulness Inventory for Sport, and the Family Cohesion Questionnaire. The proposed model was evaluated using path analysis, and indirect correlations were tested with bootstrapping. The results suggested that all direct paths to sport self-efficacy were significant except athletic mindfulness (p<0.01), and indirect paths to sports self-efficacy became significant through family cohesion (p<0.01). According to the results of this study, the proposed model had good fitness and was a major step toward recognizing the factors affecting sports self-efficacy in male athletes as it can be helpful in designing effective plans to reduce males' experienced tension and improve their sports self-efficacy.

This study aimed to the effect of sports managers' literacy on the performance of football clubs in Iranian leagues. The method of this research was descriptive-correlational. The statistical population consisted of all managers of football clubs in Iranian leagues.  267 questionnaires were  distributed among managers as the research sample.The research instruments included a questionnaire on sports managers' literacy (semi-researcher-made) and the performance of sports clubs (Shafiee et al., 2013). The tool's validity was confirmed using the opinion of experts. Smart PLS 3 software was used to analyze the data and the relationships between the variables. Findings showed that respectively, media literacy (Path coefficient: 0.88; T-Value: 7.65); Technology Literacy (Path coefficient: 0.78; T-Value: 5.87); Legal Literacy (Path coefficient: 0.76; T-Value: 5.19); Managerial literacy (Path coefficient: 0.67; T-Value: 3.50), and financial literacy (Path coefficient: 0.62; T-Value: 2.53) had significant effects on the performance of football clubs. Based on the findings, it was found that sports managers should use a variety of literacy in different areas of decision-making and face different problems to provide the ground for better success and performance of the club.

Religion, as a set of beliefs, dos and don'ts, as well as specific and generalized values, is considered one of the most effective psychological supports that is able to provide the meaning of life in every moment of life and in special circumstances with explanatory supports will save a person from suspense and meaninglessness. The present research is of a comparative causal type and its purpose is to investigate the effect of religious attitude and emotional intelligence on the aggression of professional wrestlers. Data related to religious attitude, emotional intelligence and the effect of these two on aggression were collected from 100 wrestlers using religious attitude questionnaires, Shott's emotional intelligence questionnaire and Nelson's anger questionnaire. The results of the research showed that religious attitude and emotional intelligence have an interactive effect on reducing the aggressiveness of professional wrestlers. Based on the subjects' statements, the results showed that aggression among people with high religious attitude was lower than among people with low and medium religious attitude. The results of two-variable variance analysis also showed that the interactive effect of the two components of religious attitude and emotional intelligence on aggression is statistically significant, in other words, religious attitude and emotional intelligence have an interactive effect on the aggression component of professional wrestlers.