Purpose: Today, having knowledge-based organizations and businesses is considered an important and main capital for a country and can create a competitive advantage. As a result, the aim of this study was to drawing a scientific map of the knowledge-based businesses development with a bibliometric approach. Methodology: The current research in terms of purpose was applied and in terms of implementation method was descriptive. The population of this study was the conducted research in the field of knowledge-based business development in the Scopus database from 1985 to 2023 year. The data of this study were analyzed by the bibliometric method according to the systematic approach with the two objectives of functional analysis and citation network analysis and with PRISMA protocol in VOSViewer software. Findings: The functional analysis findings showed that in the field of knowledge-based businesses development, Gambardella and McGahan had the most citations (372 times) with an article entitled Business-model innovation: General purpose technologies and their implications for industry structure. Also, authors including Crenicean, Ichijo, Kohlbacher, Markopoulos, Popescu, Sequeira, Vanharanta and Will and countries including United Kingdom, China, United States, Germany, Italy, Romania and South Korea respectively had the most research in the field of knowledge-based businesses development. In addition, the findings of the citation network analysis showed that for collaboration between authors there were 21 links, 7 keywords and 1 cluster and for collaboration between countries there were 34 links, 22 keywords and 5 clusters. Also, for co-referencing words there were 1475 links, 138 keywords and 6 clusters, which were more related to the words of business development, knowledge-based systems, innovation and knowledge management. Conclusion: The results of the present research about the knowledge-based businesses development with a bibliometric approach can have an effective role in designing and implementing programs to improve knowledge-based businesses.