Perpose: The purpose of this study was to investigate the psychometric properties of the Friendship Self-Regulation Questionnaire (SRQ-F) in students. Methodology: In a descriptive-correlation and validation study, 216 and 226 graduate students from Ferdowsi University of Mashhad selected through multi-stage sampling method. Data were collected using the Friendship Self-Regulation Questionnaire (Ryan & Connell, 1989), Basic Need Satisfaction in Relationships (LaGuardia, et all, 2002) and Subjective Vitality Scale-State level Version (Ryan & Frederick, 1997). Internal consistency, exploratory and confirmatory factor analysis and criterion validity were analyzed. Findings: The results showed that the scale had four-factor structure with the variance explained 67.20%. The confirmatory factor analysis was confirmed. The scale had good construction reliability. The criterion validity confirmed in relation to basic need satisfaction in relationships and subjective vitality in friendship (P≤0.01). Conclusion: The Friendship Self-Regulation Questionnaire (SRQ-F) had good internal consistency as well as exploratory and confirmatory validity in students. This questionnaire can be used as a valid instrument in future studies.