The theory of the Buzan’s regional security complex is one of the most important theories of regional system analysis. But the theory has some shortcomings in the analysis of regional systems such as the Middle East. This article seeks to illustrate and reform those shortcomings with a fundamental theoretical and explanatory approach. This can also provide common variables for scrutinizing the regions all over the world. In this way, it is argued that it is need and necessary adding one more variable called "problematic" to the regional security complex theory. Also It is argued that, due to the specific characteristics of each region, it is necessary to consider the other particular variables of each region. Since this study focuses on the regional system of the Middle East as a case, it is also necessary to examine two other variables, the "individual" and the "structure of the international system".