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Background: Research shows that new technologies have increased the tendency to use electronic sports in physical education activities. Studies on physical education activities and e-sports are relatively new and scattered in their focus. However, universities and professionals are growing interested in further research in this area. Aim: The purpose of this study is to systematically review the research done in e-sports and physical education. Materials and Methods: A search was made using EBSCO, Scopus, and Web of Science databases to collect information on the articles. More than 250 scientific articles from 2000 to 2024 were reviewed. The keywords used were: ("Internet sports" or "electronic sports" or "online sports" or "virtual sports" or "E-sport) and ("physical training" or "sports training" or "fitness training" or "Exercise instruction" or "Sports education" or "physical education"). After removing duplicates, 200 articles were screened by reviewing titles and abstracts, resulting in the exclusion of 100 articles that did not meet the inclusion criteria related to integrating electronic sports and physical education. The full texts of the remaining 100 articles were assessed, leading to the exclusion of 36 more articles due to insufficient data or lack of relevance, leaving 64 articles selected for detailed analysis based on their comprehensive coverage and relevance to the study. Then, the selected items were fully studied and finalized, and the items that were more complete than the others were chosen as references. Conclusion: The study identified critical organizational, technological, individual, and environmental factors influencing the implementation of e-sports. It also highlighted nine mediators’ factors essential for effective execution. Strategies like gamification, e-sport fitness challenges, cross-training, team building, health education, e-sport analysis, and smartening education were proposed to support the model's implementation. The expected outcomes of applying this model in physical education include improved cognitive skills, increased physical activity, enhanced social interaction, inclusivity, and technology skill integration. The study emphasizes that considering these factors and strategies will aid in successfully implementing the conceptual model.

Background: Physical activity affects the health of the body's organs through several processes. Apoptosis is one of the important cellular processes that play a role in maintaining the balance between cell death and tissue growth. Aim: The aim of the present study was to examine the previous findings regarding the effect of physical activity and exercise on apoptosis in order to obtain a relatively comprehensive knowledge of this effect by summarizing and analyzing the data. Materials and Methods: To collect the information of the articles, a search was made from PubMed, MEDLINE, SID, IranMedex, IranDoc, Magiran and Medlib databases. More than 80 scientific articles from 2000 to 2023 were reviewed. The keywords used were: physical activity, aerobic exercise, endurance exercise, apoptosis and cell suicide. After the review, finally 26 articles were selected. Then, the selected items were fully studied and finalized, and the items that were more complete than the others were selected as references. Conclusion: Physical activity and exercise, especially aerobic exercise, as a safe, cheap and accessible method, can reduce apoptosis through several mechanisms. The breadth of studies in this field, and the overlapping of many data, allows us to confidently introduce exercise and aerobic activity as one of the best methods of regulating body homeostasis and reducing apoptosis.