Because of the many geopolitical potentials and communicational capabilities of ECO region, members could expand the convergency based on this organization which plays a key part in development of members and expandsion of peace and security. Due to studying the effective factors of Regional Organizations (ROs), particularly those of ECO, it seems that the resultant of internal and external regional forces fails to empower ECO members’ integration, but with a review of other successful ROs, it is revealed that they have a process mechanism which strengthens convergent forces and mitigates the divergent ones with institutionalized tools and active positive diplomacy. Based on qualitative analysis conducted on desk and in interview with geopolitical experts; this study seeks to answer the question: what are the effective factors of formation and evolution of ROs in general and those of ECO in particular? The results of the research indicate that creating a regional consciousness and a common understanding of capabilities and geopolitical values in ECO region has failed to reach maturity. The structure of competition between members represents the lack of regional common understanding on these values. Despite the progress, the evolution of structural and organizational development of ECO and its essential documents; the weakness of policy to create coordination in multilateral diplomacy, the weakness of domestic political institutions, the weakness of organizational structure, especially in staff and technical expertise, and eventually incompetency of organization and human resources, especially in the Secretariat, have caused many inefficiencies and structural weaknesses in ECO.