درخت حوزه‌های تخصصی

Purpose: The world is getting old. Alzheimer's disease is a progressive disease, which in case of no intervention, this ratio reaches 4 more advanced stages in people over 85 years old. Some methods have shown that they can be effective in preventing and slowing down the course of the disease. The purpose of this study was to investigate the role of aerobic exercise program on the quality and some physiological parameters related to sleep in the elderly with Alzheimer's disease. Method: 22 elderly people with Alzheimer's disease were randomly divided into two groups of 11 people: aerobic exercise and control. The subjects in the aerobic training group practiced three sessions every week for twelve weeks and each session lasted for 45 minutes. The sleep quality of the subjects was evaluated by the Pittsburgh Sleep Quality Questionnaire (PSQI). Physiological variables related to sleep (TG, TC, LDL, HDL) were also measured by blood sampling before and after twelve weeks of aerobic exercise Results: The results showed that the sleep quality of the subjects improved by 31% in the Pied Heroi group, which was statistically significant. In addition, there was a significant improvement in the changes of TG (p=0.034), TC (p=0.017), LDL (p=0.006), and HDL (p=0.016) in the aerobic training group. The results of the independent t test also showed that there was a significant difference in sleep quality between the aerobic training and control groups. However, no relationship was observed between changes in sleep quality and changes in physiological variables related to sleep. Conclusion: It can be concluded that twelve weeks of aerobic exercise improves sleep quality along with some physiological parameters related to sleep in the elderly with Alzheimer's disease and will be useful as a way to treat sleep problems in the elderly.

Background: Since the outbreak of COVID-19 virus and the rise in concerns, researchers have been investigating risk factors of this disease. One of the factors affecting the hospitalization of influenza patients is high BMI. Due to the relation between COVID-19 disease and influenza. Aim : the purpose of this study was to investigate the effect of BMI on the infection and severity of COVID-19 patients. Materials and Methods: BMI of 126 men was calculated and three groups of "appropriate weight", "overweight" and "obese" were identified. Then, the prevalence and severity of their disease were recorded. For data analysis, chi2 test was used in SPSS 26 software at a significance level of P = 0.05. Results: Prevalence of COVID-19 infection in the group with “appropriate weight”, ”overweight” and “fat” were 56%, 61% and 58%, respectively. Mild infection was reported in the three groups, 27%, 27% and 26%, respectively; Moderate infection was 22%, 26% and 26%, respectively; and severe infection was 7%, 8% and 5%, respectively. Therefore, there was no significant difference between their infection and the severity of infection in groups ( P ˃.05). Conclusion: Obesity has negative effect on the body's immune response and lung function. The hospitalization rate for influenza is higher in this group. But in infection of COVID-19 and severity of this disease, no significant difference was observed between men with different BMI. However, due to the relation between obesity, cardiovascular disease, diabetes, and the vulnerability of these patients to the COVID-19 virus, serious attention is necessary to prevent these individuals from COVID-19.