Reflective practice and noticing can be regarded as two essential concerns for novice teachers’ survival and development in their first practices. Therefore, this study was an attempt to explore how reflective practices activate novice English as a Foreign Language (EFL) teachers’ noticing. To that end, we conducted an instrumental case study to explore the role of reflective practice among Iranian novice EFL teachers in activating their noticing. An inductive-deductive thematic analysis of the data collected through teachers’ portfolios and semi-structured interviews indicated that novice teachers’ noticing could be activated and sharpened through teachers’ personal, cognitive, and professional developments addressed by reflective practice. Furthermore, the findings showed that there are relationships among novice teachers’ personal, cognitive, and professional developments and the components of teacher noticing, including framing, perceptual activities and exploration, and interaction, leading to sharpening novice EFL teachers’ noticing. Hence, it can be concluded reflective practice can activate novice EFL teachers' noticing, impacting their professional development through framing, interaction, perceptual activities, and exploration. The study has implications for EFL teacher education programs, where teacher educators can help teachers develop critical reflection skills to address problems in their classrooms.