The Sassanid era is one of the most brilliant in the Iranian civilization in terms of various arts development. The coastal areas of the Caspian Sea, especially Mazandaran, has long been the site of artistic manifestation with countless examples of art works kept in different museums inside and outside the country. The Sassanid art particularly depict life and glory of the kings. With a deep insight into the works, one can easily find the use of a vast array of birds, animals, plants, gods and mythological beings in symbolic ways. After reviewing and researching all the works created in the Sassanid period, a common feature attracts opinions, and that is the similarity and harmony of decorative motifs in all of these works, especially bas-reliefs, metal wares, fabrics and seals. The purpose of this research is to investigate the images of sacred animals on the Mazandaran artifacts of the Sassanid period, in response to the question of what is the relationship between the designs of sacred animals and the motifs on discovered metal works of Mazandaran. The results of this study clearly show that in most of the concepts and representations in the works produced in every part of this civilization, a common goal was pursued, and it is a struggle against evil forces. The symbolic emblems of sacred animals in Iran can be found in close connection with the beliefs and religions of that era, some of which are manifested in the form of boar and lion in the body of gods and goddesses.