علیرضا بابایی مزرعه نو

Purpose: The purpose of the present research was to investigate the effect of eight weeks of progressive resistance exercise and a subsequent detraining period on the indicators of muscle fiber shortening (FS%) and the relative wall thickness (RWT) of the left ventricle in low-mobility women. Method: This semi-experimental study was conducted in a field-laboratory setting. A total of 32 sedentary women, who met the criteria for participation and were able to engage in the exercise protocol, were randomly assigned to two groups: 1) Resistance training group (16 participants), and 2) Control group (16 participants). Anthropometric characteristics, body composition, and structural indices such as left ventricular muscle fiber shortening percentage (FS%) and relative wall thickness (RWT) were measured using an echocardiography device at three intervals: before the start of training, at the end of 8 weeks of training, and after a 4-week detraining period. The training protocol was implemented over 12 weeks, consisting of 8 weeks of training with three sessions per week, followed by 4 weeks of detraining. Data were analyzed using independent t-tests and repeated measures analysis of variance (ANOVA) at a significance level of p < 0.05, using SPSS version 21. Results: The results showed a significant difference in FS% between pre-test and post-test measurements for both the experimental and control groups (p < 0.05). Additionally, a significant decrease in FS% was observed in the training group during the detraining period (p < 0.05). Similarly, a significant change in RWT was found between pre-test and post-test measurements in both groups (p < 0.05), and significant changes in RWT were also observed during the detraining period in the training group (p < 0.05). Conclusion: Based on these findings, it can be concluded that 8 weeks of resistance training led to beneficial changes in the structure and function of the heart in sedentary women. However, the 4-week detraining period resulted in negative effects on these adaptations. Therefore, it is recommended that individuals engage in regular and structured resistance training to maintain these positive adaptations.

Fatigue is a common and debilitating symptom among older adults, significantly impacting their quality of life and functional capacity. The relationship between serotonin and fatigue in aging is complex, involving multiple neurobiological pathways that influence sleep, mood, cognitive function, and energy metabolism. Understanding these mechanisms is crucial for developing effective management strategies. This review aims to elucidate the role of serotonin in the development of fatigue in elderly individuals and evaluate potential therapeutic strategies to mitigate this condition. A comprehensive review of recent literature was conducted, focusing on the neurobiological mechanisms linking serotonin to fatigue, the efficacy of pharmacological and non-pharmacological interventions, and future research directions. Studies were selected based on their relevance to serotonin’s role in aging and fatigue management. Serotonin plays a critical role in regulating various physiological and psychological functions that impact fatigue. Age-related declines in serotonin synthesis, receptor sensitivity, and transporter function contribute to increased fatigue through disrupted sleep, mood disorders, cognitive decline, and altered energy metabolism. Pharmacological treatments, including selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs), have shown efficacy in alleviating fatigue related to depression and chronic pain. Non-pharmacological interventions, such as cognitive behavioral therapy (CBT), exercise, sleep hygiene, and dietary modifications, are also effective in managing fatigue. Combining these approaches may offer the best outcomes for elderly patients. Addressing fatigue in older adults requires a multifaceted approach that integrates both pharmacological and non-pharmacological strategies. Personalized treatment plans considering individual patient profiles and preferences can enhance therapeutic efficacy. Future research should focus on exploring novel therapeutic targets within the serotonergic system, developing personalized medicine approaches, and evaluating the long-term impact of combined therapies.

The purpose of this research was to investigate the effectiveness of advertisements and equipment on attracting customers in sports halls of Yazd province. This is a descriptive research, the statistical population of this research was all the customers of the educational sports halls of Yazd province in the number of 3000 people, of which 240 people were selected as available. To measure the data, Moradi's 1392 customer attraction questionnaire, the advertising role questionnaire (Niknam, 1392) was used. During the distribution and completion of the questionnaire by the respondents, the researcher was present and made it possible to give the necessary explanations to the respondents regarding the purpose of the research, its importance in the way of answering the questions, after completing and returning 240 questionnaires, the results It was analyzed using descriptive and inferential statistics such as (regression). Statistical analyzes were performed using SPSS software version 21 and at an error level of less than 0.05. Finally, the results showed that advertising plays a significant role in attracting customers in sports halls of Yazd province.