This study aimed to investigate the effectiveness of cognitive hypnosis therapy on sexual desire and marital satisfaction of women. The study's design was semi-experimental and pre-test and post-test with the control group. The statistical population included all women referred to Babolsar Eltiam psychological clinic and then 22 women were selected by available sampling method and randomly assigned to experimental and control groups (11 women for each group). The experimental group was received cognitive hypnotherapy for 11 sessions and each session lasting 90 minutes; while the control group did not receive any intervention during this research. Both groups compeleted the Apt and Halbert (HISD) Sex Desire Scale and Enrich Marital Satisfaction Scale (ESQ-47) in two stages of pre-test and post-test. The collected data were analyzed using covariance analysis statistical method. The results of covariance analysis showed a significant difference between the performance of both experimental and control groups in the scores of developmental functions of Sexual Desire and marital satisfaction in post-test stage (P<0/001) Based on the findings of the study, it can be concluded that cognitive hypnosis therapy is effective in increasing marital satisfaction and improving women's Sex Desire. Consequently, marital satisfaction and improve women's Sex Desire promote by cognitive hypnosis therapy.