Objective: Addiction is a physical-mental illness that, due to its progressive nature in all aspects of life, endangers the health of the individual, family and society. In order to prevent and resolve this destructive phenomenon, it is necessary to provide and implement comprehensive and appropriate programs in the rural area. Therefore, the aim of the present study is to determine the predictors of substance abuse of rural immigrant. Method: The statistical population included all addicted prisoners who migrated from rural to urban areas. Using cluster sampling method, 360 people were selected as the study sample. Descriptive statistics and logistic regression were used to analyze data. Result:The results showed that only the quality of life component can predict the drug abuse of migrant rural men and women, while the components of access to facilities, rural management performance, and individual participation, as well as marital status, age and education cannot predict their substance abuse (p <0.05). Conclusions: According to the results of the present study, since the quality of life is a predictor of substance abuse in migrant villagers, and this problem, in fact, indicates the basic infrastructural problems in preventing the migration of villagers and their substances abuse, related planning and policies in the field of social health are suggested in this regard.
