The purpose of the present study was to predict self-efficacy of women with breast cancer based on quality of life, religious orientation, resilience, death anxiety, psychological hardiness and perceived social support. The research method was descriptive and regression type. The statistical population in this study included all patients with breast cancer referring to Cancer Institute of Imam Khomeini and Milad hospitals in Tehran in 2018. Purposeful sampling method was used to select the sample. In this way, 300 patients with breast cancer patients were selected based on the criteria for entering and leaving the research. The research tool was a general self-efficacy questionnaire of Sherer et al. (1982), multi-dimensional perceived social support questionnaire (Zimt et al., 1989), Allport Religious Orientation (1967), Kobasa Psychological Hardiness Questionnaire (1979), Templar's Death Anxiety Scale (1970) ), The Conor-Davidson Resilience Questionnaire (2003) and the World Health Organization Quality of Life Scale (1996). Regression analysis was used to analyze the data. The results of data analysis showed that factors of quality of life, religious orientation, resilience, death anxiety, psychological hardiness and perceived social support have 21% ability to predict self-efficacy. The factors of quality of life, resilience, psychological hardiness and social support with self-efficacy are positive at 5% confidence level, and the positivity of these coefficients actually indicates that increasing these factors increases self-efficacy (p <0.05). Death anxiety also has a significant negative correlation with self-efficacy (p <0.05).
