The relation of familly factors in patients with anxiety disorders is a new approach with therapeutic applications. The aim of this research was to Prediction of children’s anxiety based on The mother’s corona anxiety and negative affect. The research method was applied in terms of purpose and in terms of data collection descriptive-correlation. The statistical population of study consisted of all mothers with Corona anxiety going to Aramesh counseling centers at Urmia City. 63 people among them were selected using available sampling method. All subjects completed the Spence children’s anxiety queistionnair/a (SCAS(, Scale of Positive and Negative Experience (SPANE) and corona anxiety scale (CDAS). Data analysis was done by SPSS23 software with Pearson correlation coefficient and multiple regression methods. The results indicated that the mother’s corona anxiety and negative affect predict children’s anxiety positively and significantly (P<0.01). These findings can be effective in the clinical and counseling settings.