endurance performance

Background: Gene polymorphisms are related to athletic performance. Angiotensin converting enzyme gene polymorphism is essential in identifying talent and guiding adolescents to appropriate sports. Aim : The aim was to investigate the relationship between the angiotensin gene and endurance performance of novice adolescent wrestlers in Ardabil. Materials and Methods: Subjects were 15 Amateur adolescent wrestlers in Ardabil (age: 13.07±1.53 years, height: 164.60±10.68 cm, weight: 60.14±6.32 kg, BMI: 22.22±4.98 kg/m 2 ) with three-year wrestling. Chest and thigh muscle endurance, abdominal fat percentage and cardiovascular endurance, chest press, and squat muscle endurance were measured. ACE polymorphism was determined using tetra-ARMs polymerase chain reaction (PCR) and compared direct DNA sequencing in salivary samples. Chi-square and ANOVA were used to compare frequencies and their relationship with performance indicators. Results: ACE DD genotype frequency was higher in novice adolescent wrestlers, and there was a significant difference between ACE polymorphism frequency ( P =0.008). There was a significant difference between ACE genotype distribution with endurance performance of pectoral and triceps ( P =0.004) muscles, body composition ( P =0.0001), and Vo 2 max ( P =0.0001). There was a significant difference between body composition and Vo 2 max of Amateur adolescent wrestlers with ACE DD ( P =0.0001), ACE II ( P =0.0001), and between body composition and Vo 2 max with ACE II ( P =0.0001), ACE DD ( P =0.0001), and ACE ID ( P =0.0001). In body composition, ACE II was significantly higher compared to ACE DD ( P =0.0001) and compared to ACE ID ( P =0.0001). Also, in Vo 2 max, ACE II was significantly higher compared to ACE DD ( P =0.0001) and compared to ACE ID ( P =0.0001). Conclusion: Findings showed the superiority of ACE DD polymorphism and its relationship with the endurance performance of novice adolescent wrestlers in Ardabil. ACE DD polymorphism is probably essential in wrestler success. Other research with more subjects and other genes is important.

Purpose: This study aimed to investigate the relationship between gut microbiome composition, athletic performance, and post-exercise recovery in endurance athletes following probiotic supplementation.  Method: In this randomized, double-blind, placebo-controlled study, 40 male endurance runners (age: 28.3 ± 5.2 years) were randomly assigned to either a probiotic (n=20) or placebo (n=20) group for 8 weeks. The probiotic group received a daily supplement containing a blend of Lactobacillus acidophilus, Bifidobacterium lactis, and Lactobacillus plantarum (20 billion CFU total). Fecal samples were collected before and after the intervention and analyzed using 16S rRNA gene sequencing. Athletic performance was assessed through VO2max testing and time to exhaustion. Recovery was evaluated by measuring delayed onset muscle soreness (DOMS) and creatine kinase (CK) levels. Results: The probiotic group showed a significant increase in gut microbial diversity (Shannon index: p<0.01) and relative abundance of beneficial bacteria such as Bifidobacterium and Lactobacillus (p<0.001). Significant improvements were observed in VO2max (4.7%, p<0.05) and time to exhaustion (7.2%, p<0.01) in the probiotic group compared to placebo. The probiotic group also demonstrated reduced DOMS (23%, p<0.05) and lower peak CK levels (18%, p<0.01) relative to the placebo group. Multiple regression analysis revealed that changes in Akkermansia muciniphila and Bifidobacterium abundances were significant predictors of performance improvement (R² = 0.68, p<0.001). Conclusion: This study provides evidence that gut microbiome modulation through probiotic supplementation can enhance athletic performance and accelerate post-exercise recovery in endurance runners. These findings suggest that targeted manipulation of the gut microbiome may be a novel strategy for improving sports performance and recovery.