Leptin

Purpose: the etiology of children obesity can be varied. Adipose tissue is an active tissue that secretes proteins such as TNF-α, IL-6, leptin, and adiponectin. The purpose of this study was to investigate the effect of short-term sprint interval training on serum levels of adiponectin, leptin, TNF-α, IL-6, insulin, and lipid profile in overweight boys. Method: a number of 30 overweight male students (with a mean age of 9.93±0.2 and BMI of 27.73±0.2) were randomly assigned to the control group (n=15) and sprint interval training (n=15). The subjects of the experimental group did the training for eight weeks, as the control group was engaged in doing their daily activities without intervention. Measurement of anthropometric indices and fasting blood collection were performed (to measure insulin, leptin, adiponectin, TNF-α, IL-6, cholesterol, LDL, HDL and TG) one day before and one day after the training program. Results: the results of the present study indicated that 8 weeks of sprint interval training significantly decreased weight and BMI in overweight children (P<0.001). In addition to weight and BMI reduction, levels of TNF-α, IL-6, leptin, insulin, cholesterol, triglyceride, and LDL significantly reduce the following eight weeks of the sprint interval workout (P< 0.001 for all), while adiponectin and HDL levels increase (P<0.001, P<0.01, respectively). Conclusions: in general, the present study demonstrate that sprint interval training which is a new way of physical activity exerted a positive effect on most of components contributing to children obesity.

Purpose: the etiology of children obesity can be varied. Adipose tissue is an active tissue that secretes proteins such as TNF-α, IL-6, leptin, and adiponectin. The purpose of this study was to investigate the effect of short-term sprint interval training on serum levels of adiponectin, leptin, TNF-α, IL-6, insulin, and lipid profile in overweight boys. Method: a number of 30 overweight male students (with a mean age of 9.93±0.2 and BMI of 27.73±0.2) were randomly assigned to the control group (n=15) and sprint interval training (n=15). The subjects of the experimental group did the training for eight weeks, as the control group was engaged in doing their daily activities without intervention. Measurement of anthropometric indices and fasting blood collection were performed (to measure insulin, leptin, adiponectin, TNF-α, IL-6, cholesterol, LDL, HDL and TG) one day before and one day after the training program. Results: the results of the present study indicated that 8 weeks of sprint interval training significantly decreased weight and BMI in overweight children (P<0.001). In addition to weight and BMI reduction, levels of TNF-α, IL-6, leptin, insulin, cholesterol, triglyceride, and LDL significantly reduce the following eight weeks of the sprint interval workout (P< 0.001 for all), while adiponectin and HDL levels increase (P<0.001, P<0.01, respectively). Conclusions: in general, the present study demonstrate that sprint interval training which is a new way of physical activity exerted a positive effect on most of components contributing to children obesity.

Objective: Plasma follistatin and leptin proteins are important indicators in energy and metabolism regulation that also affect body weight. The aim of this study was to investigate the effect of resistance training with and without blood flow restriction on serum follistatin and leptin levels in inactive obese girls. Materials and Methods: Thirty inactive obese girls with an age range of 20 to 28 years participated in this study. The subjects were randomly divided into 3 groups: resistance training with blood flow restriction and resistance training without blood flow restriction, and a control group (10 subjects in each group). Data analysis was performed using paired t-tests and one-way ANOVA at a significance level of less than 5%. Results: After 12 weeks of participation in sports activity, follistatin levels in both resistance training groups with and without blood flow restriction increased significantly after training (p<0.05). On the other hand, leptin levels decreased significantly in these groups after training interventions (p<0.05). Regarding the main effect of groups, the results showed that there was a significant difference between the types of resistance training and the control group in follistatin (P=0.036) and leptin (P=0.015) levels. Conclusion: The findings indicate that resistance training can lead to an increase in plasma follistatin levels and a decrease in leptin in inactive obese girls. It is recommended that obese individuals use such resistance training with blood flow restriction as a non-invasive, low-cost, and side-effect-free method to promote health and lose weight