Although the importance of intercultural competence (IC) training has been increasingly recognized in recent scholarly reviews, home-based approaches invite further investigation in this paradigm. This study aims to make a contribution by exposing a domestic context to assess IC development through using qualitative and quantitative methods. To do so, sixty two undergraduate EFL student-teachers were guided to conduct two either on-line or face to face reflective ethnographic interviews over a sixteen-week course of cross-cultural communication. The quantitative findings obtained from the Intercultural Development Inventory (IDI) questionnaire showed significant increase in participants’ Perceived Orientation (PO) and Developmental Orientation (DO) after the course. Qualitative findings also revealed significant growth, provoking some new perceptions, and emphasizing the student-teachers’ positive responses to both IDI assessment and the intercultural interactions. The exploratory analysis of the participants’ reports on the ethnographic interviews resulted in seven emerged themes which conceptually matched the traditional IC model. Therefore, the study shows that using reflective ethnographic interviews in a mixed methods design is helpful in developing and assessing student-teachers’ IC.