Purpose: The aim of this study was to compare the effectiveness of family therapy program based on attachment and emotion on anxiety disorder and behavior of gifted adolescents. Methodology: The research method was quasi-experimental with pretest-posttest design with two experimental groups. From the statistical population of students studying in gifted schools in Tehran, 40 people were randomly selected and randomly assigned to two groups. The research questionnaire included Achenbach (1994) internalization problems. Family therapies based on attachment and emotion was applied for ten sessions of the research groups. Research data were analyzed using repeated measures analysis of variance and SPSS software. Findings: The results of repeated measures analysis of variance showed that the post-test scores of anxiety disorder and behavior in the attachment-based family therapy group were significantly lower than the emotion-based family therapy group (P10.001). Couple comparison also showed that the effect of attachment-based family therapy program on anxiety disorder and behavior is stable (p <0.01). Conclusion: The results showed that the effect of attachment-based family therapy was significantly greater than emotion-based family therapy. In addition, attachment-based family therapy has a significant and lasting effect on reducing the behavioral disorders of gifted adolescents. Therefore, in order to improve the mental state and especially the anxiety disorder and behavior of gifted adolescents, an attachment-based family therapy program can be used