Since the advent of the Islamic Revolution in Iran, the country has been continuously subject to severe sanctions by the Western countries, especially the United States. In all these years, the U.S. sanctions did not affect Iran’s economy much, due to the fact that the two countries have no formal relations and as a result, their economies are not, by any means, interdependent. However, Iran’s economy has been reliant on extensive interactions with the European countries; the EU sanctions against Iran since 2011, therefore, have harshly affected Iran’s economy and caused adverse social impacts on Iranian lives. In the shadow of Iran’s dark image in the eyes of the world, one issue that has remained overshadowed by the discussions on the impact and effectiveness of the sanctions, is the severe human rights crises left by the EU sanctions. The key question is what have been the human rights and humanitarian consequences of the EU sanctions for Iran, and how serious have these consequences been for the country? As the author argues in this paper, EU economic sanctions against Iran are considered violations of the three main generations of human rights and are therefore unwarranted. Given this, the resumption of sanctions since 2018 would lead to a human rights disaster in Iran. The effect of these sanctions will not affect the Iranian government, but the Iranian civilians, especially the vulnerable, which will undermine their human dignity.