The present study aimed to identify the organizational factors affecting the growth and success of academic spin-offs. The research was conducted based on a mixed method design and the study population consisted of experts of incubation centers and spin-offs. The participants were selected using purposive sampling in the qualitative part and random stratified sampling in the quantitative part. Data coding was employed to analyze qualitative data and exploratory and confirmatory factor analysis were used to analyze quantitative data. The qualitative results indicated that 26 organizational factors affected the growth and success of academic spin-offs. The quantitative results showed that “business planning to convert ideas into products” and “applicability of academic research” predict the highest and the lowest variance of the dependent variable, respectively.
