مهسا غفارزاده

objective: The aim of this study was to determine the effect of group therapy in cognitive-behavioral manner on anxiety, stress and despair of Multiple sclerosis patients in Tehran. Method: This study was a quasi-experimental study with pre-test-post-test with control group. Twenty patients referred to the available medical centers were selected as a sample and randomly assigned to two experimental and control groups. In this study, Kalmogorov-Smirnov, Levene and Covarians tests were evaluated with Spss software. also, Beck Anxiety Inventory Questionnaire, Cohen's Perceived Stress Questionnaire (PSQ) and Beck's Hopelessness Scale questionnaire were applied to collect data. Results: The results of the present study showed that there is a significant difference between the experimental and control group of anxiety, stress and despair with 95% confidence level. Therefore, all three main hypotheses were confirmed and the null hypothesis was rejected. In reducing anxiety, stress, and despair in MS patients, group therapy is effective in a cognitive-behavioral manner. Conclusion: Cognitive-behavioral group therapy reduced stress, anxiety and despair in patients with MS and improved mental health of these patients. Therefore, this treatment method can be considered a treatment in clinics.