The complexity of the competitive business environment has highlighted the need to be aware of the organization's strengths and weaknesses and to continuously improve processes. Therefore, managers are looking for a solution for performance measurement of their organization to be able to promote and improve their organization. Evaluating the performance of listed companies in the stock exchange organization is important because in addition to the managers of the organizations, stock traders can also evaluate the companies and make the necessary decisions about holding, selling or buying the shares of these companies in a timely manner. One of the organization's performance measurement solutions is to use financial ratios. Given that a separate study of financial ratios does not provide a correct view of the efficiency of the organization, so the aggregation of the effect of financial ratios seems to be effective. DEA and MCDM are suitable because they enable the achievement of performance index by considering several factors simultaneously, so the performance obtained from this method is reliable. the main purpose of this study is to ranking pharmaceutical companies in the Tehran Stock Exchange between the years 2018 and 2020 using DEA approach and MCDM to provide a single ranking through the Copeland method.