Purpose: Regarded to the importance of professors' effectiveness, the purpose of this study was structural modeling of the impact of entrepreneurial thinking and professional commitment on professors' effectiveness with the mediating role of satisfaction from organizational climate among professors of Islamic Azad University of Urmia Branch. Methodology: This study in terms of purpose was applied and in terms of implementation method was cross-sectional from type of quantitative. The research population was the professors of the Islamic Azad University of Urmia Branch in the 2020-21 academic years, which based on the Cochran's formula the sample size was estimated 227 people who were selected by stratified random sampling method according to different colleges. The research instruments of the present study were the Questionnaires of entrepreneurial thinking (Scarborough & Zimmerer, 1990), professional commitment (Allen & Meyer, 1990), professors' effectiveness (Salimi & Ramezani, 2014) and satisfaction from organizational climate (Bontis, 1998). Data were analyzed by structural equation modeling in SPSS-21 and SmartPLS-2 software. Findings: The results showed that entrepreneurial thinking and professional commitment had a positive and direct effect on satisfaction from organizational climate and professors' effectiveness and satisfaction from organizational climate had a positive and direct effect on professors' effectiveness. Also, entrepreneurial thinking and professional commitment had a positive and indirect effect on the professors' effectiveness with the mediating role of satisfaction from organizational climate (P<0.01). Conclusion: According to the results of this research, to improve the professors' effectiveness can be used by promoting entrepreneurial thinking, professional commitment and satisfaction from organizational climate.
