The Islamic State of Iraq and the Levant, or ISIS, gained considerable power over a short period of time and at the height of its power, Al-Baghdadi controlled more broadly than Britain And it was thought that for many years it could survive. But by the Iraqi and Syrian armies and the popular forces of these two countries and with the help of the IRGC, this terrorist group lost all of its occupied territories in Iraq and Syria. So, its collapse is important and will have significant effects on the geopolitics of the Middle East. The main subject of this article is the same. The main question of the paper is how would the ISIS collapse affect Middle Eastern politics? The answer to this question will be presented in six sections, all of which relate to the probabilities following the fall of ISIS in the Middle East. The research method of article is based on explanation method.