Many people travel in search of life-altering experiences, which, in the form of epiphanies, lead to a profound and positive transformation in their daily lives. This paper focuses on the intersections of religion, spirituality, and wellness, and how similar experiences in these areas can be interpreted through viewing people through the lens of the human “soul”. After briefly defining religion, spirituality, and wellness, attention is turned to the medicalization of religion and spirituality in the form on wellness. The relationships between the soul, spiritual health, and travel are then briefly discussed before concluding.