In the 21st century, the meaning of places is essential to people. Meanings have gained symbolic importance through tourism heritage. Tourism is a powerful force in shaping the world and our understanding of different cultures, people, and places. This research investigates the complexities of religious tourism and the management of religious destinations. It obtains criteria for managing religious goals with a detailed look and uses the descriptive-analytical method based on library documents and the opinion of research experts. Then, using research experts and ISM-PLS hybrid approach, a three-level framework for managing religious goals in Yazd city has been presented and analyzed. The results showed that the government's decisions and actions were the most effective criteria. The ultimate goal was to create a sense of trust and security among religious tourists. It is hoped that the findings of this research will be a starting point for managing religious tourism destinations and a guide for examining the complexities of Islamic tourism destinations and their management.