Social media is an interactive technology, that came into reality out of fun for interaction, but it has advanced towards a powerful tool for instruction globally. However, despite its use and relevance, the utilization and its self-efficacy to learning have not been significantly be aware of. Therefore, this study investigate social media in the context of area of study for learning and its self-efficacy. Descriptive research of cross-sectional survey method and purposive sampling was used to sample 2,458 postgraduate students across the universities in South-west, Nigeria. Through administering the instrument of study questionnaire. The findings revealed that there were no significant differences between postgraduate students to use social media for learning based on their area of study t(2,2456)=5.93;p>0.05. Self-Efficacy, t(2,2454)=0.56;p>0.57. The study concluded that postgraduate students’ have positive perception towards social media. It was however recommended that the use of social media should be encouraged in facilitating learning.