The growth and development of urban settlement have always been accompanied by industrial activities. Previous experience shows that after industrialization of the countries and the local selection of their industries in big cities, these cities have faced with enormous work force immigration and have observed severe changes in their urban system. These changes are mostly caused by the execution of the growth pole policy and the concentrated distribution of industries in these countries’ centers. In Iran, after the solar 1340s (1961-1971C.E.), we have observed severe changes in urban system that its coincidence with the country’s industrialization requires lots of considerations. The execution of the industries’ establishment prohibition in a distance of 120 kilometers from Tehran is the appearance of one of the presented means in this era. But we still witness the big industries’ presence by 90% in Tehran in 1981. This paper is to proceed with the method of industries’ distribution in Iran by analyzing the place of small and big industries separately in cities with a population of more than 100.000 members. The results of the analysis express that 55% of the 28663 active workshops registered in cities with a population of more than 100.000 members are selected their local in only 7 cities namely Tabriz, Mashhad, yazd, Isfahan, Qom, Tehran, and Karaj, which shows a kind of disproportion in the industries’ distribution across the country. Also, more than 90% of the existing active industrial workshops in cities with a population of more than 100.000 members have been in the range of less than 50 employed industries that included 50% of the employed members in the industry sector.