The study tried to examine the possible effect of multimedia materials on augmenting listening skills of girls in Meheaval higher secondary school, Karaj city. The next purpose was to detect whether there is a meaningful relationship between students’ attitudes towards using multimedia materials and teaching listening skills. The participants of this study were 60 second-year high school (EFL famale students) in the second semester of 2016 academic year. The homogeneity of the participants was ensured through application of the Oxford Placement Test (OPT, 2001). The materials was comprised of students’ textbook and Listening Assisted Multimedia. Three types of instruments which were utilized namely, listening comprehension pre-test, post-test, and a listening assisted multimedia questionnaire. Independent samples t-tests and regression coefficients were applied to determine whether there were significant inter and intra-group differences. The results showed evidence that multimedia materials significantly enhanced EFL learners’ listening achievement. It was also found that the attitude to the use of multimedia had a statistically significant impact on explaining the changes in learners’ listening skill. Based upon the findings of the study, it is recommended that the English instruction should be integrated to the English instruction listening course. Key words: Multimedia, Listening, Listening Assisted Multimedia Questionnaire