alkaline phosphatase

Purpose: Osteoporosis is a decrease in bone density among older adults that can cause painful fractures and disability. One of the most important effective non-pharmacological interventions is having appropriate and continuous physical activity.  The aim of this study was to investigate the relationship between serum calcium and alkaline phosphatase with femur bone mineral density in active and inactive men. Method: This study was semi-experimental. 35 active and 35 inactive elderly men aged 65 to 80 years with medical records were selected. Anthropometric characteristics, serum calcium and alkaline phosphatase of subjects were used as effective indicators of osteoporosis. Pearson's correlation coefficient was used to find the relationship between femur mineral density and serum calcium and alkaline phosphatase, data analysis was done using SPSS version 26 Software. Results: The results of this research showed that in both groups of active and inactive men, there was a significant relationship between serum calcium and alkaline phosphatase and femur mineral density (P≤0.05). No significant relationship was found between the height index and mineral density of the femur (P≥0.05). Conclusions: In general, the results show that there is a significant relationship between bone density and weight, age, calcium, phosphorus, and serum alkaline phosphatase of all subjects, and the effect of exercise on other bone density indicators can be investigated.

Purpose: The activity of plasma liver enzymes is intensified under the influence of sports activities, which is affected by the duration, intensity, type and method of training. The purpose of this study was to investigate the effect of a special endurance training session on the activity of serum alkaline phosphatase and aspartate aminotransferase liver enzymes in inactive young men. Methods: In this semi-experimental study, 16 young inactive men were purposefully selected and examined in two groups (experimental and control). The experimental group performed Bruce's protocol after preliminary warm-up. Blood samples were collected before the test, immediately after the test, 24 hours and 48 hours after the test from both groups at the same time, and the amount of serum ALP (Alkaline Phosphatase) and AST (Aspartate Transaminase) enzymes were measured using an Auto analyzer. Statistical analysis of the data, independent T-test was used to compare the results of two groups and Bonferroni's post hoc test was used to determine the difference between different stages of sampling with a minimum significance level (P≥0.05). Results: The results of the independent T-test in the comparison between the groups showed that there is a significant difference between the two groups in the amount of ALP enzyme in the time intervals immediately after the activity (P≥0.020), but in the time intervals of 24 (P≥0.177) and 48 hours (P≥0.136), there is no significant difference between the two groups after the activity. The results of the independent T test did not show any significant changes in the amount of AST enzyme in any of the time intervals in the comparison between groups. Conclusion: Fatigue-inducing sports activity leads to an increase in the amount of enzymes, ALP, this increase can be a sign of damage to liver cells or heart muscle. Considering the role of recovery in liver damage, it seems that by considering enough rest time, it is possible to help improve the adaptation process while preventing the occurrence of muscle and liver damage