Various infectious diseases have plagued humankind and killed millions throughout history. Crisis management by governments has been crucial in such emergencies. This study aims to examine the method of crisis management caused by epidemics, especially Corona in Iran, and seeks to discover the policies and measures which have been taken by governments to prevent the spread of diseases and treat these diseases since the Qajar period. In this research, which was carried out by historical method and with a descriptive-analytical approach, to collect data, documents related to the subject, identification, study, and required information were extracted and indexed. Findings indicate that the policy-making process has been better and more effective by passing of time. Thus, the minimum programs implemented by the government were not successful for various reasons in the Qajar period, but infectious diseases were mainly controlled due to the compulsion to implement health regulations in the Pahlavi period. Great strides have been made in preventing the spread of infectious diseases after the victory of the Islamic Revolution in Iran. Since the outbreak of corona disease, various measures have been taken to control the disease, which has helped curb public awareness and participation to a large extent, and Iran is now on the verge of producing the corona vaccine and launching it on the market.
